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The development of drug-resistant cancers is considered to be the most significant obstacle to the cure of cancer today. Nearly half of all patients with cancer suffer from tumors that are intrinsically resistant to chemotherapy, and most of the remaining half develop drug resistance during the course of their treatment. This book reviews the mechanisms and clinical implications of drug resistance in cancer with unrivaled authority. The authors, who are among the leading clinicians and investigators in the field, cover topics of current clinical concern, including multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and hematopoietic support.
  • ISBN13: 9780521473217
  • Publisher: Cambridge University Press
  • Pubilcation Year: 2014
  • Format: Hardcover
  • Pages: 00340
SeriesCancer: Clinical Science in Practice
Publication DateMarch 26, 1998

Drug Resistance in the Treatment of Cancer

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